cliProfiler

An easy and fast way to visualize and profile the high-throughput IP data. This package generates the meta gene profile and other profiles. These profiles could provide valuable information for understanding the IP experiment results.

The cliProfiler package extension

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Cross-linking immunoprecipitation (CLIP) is a technique that combines UV cross-linking and immunoprecipitation to analyse protein-RNA interactions or to pinpoint RNA modifications (e.g. m6A). CLIP-based methods, such as iCLIP and eCLIP, allow precise mapping of RNA modification sites or RNA-binding protein (RBP) binding sites on a genome-wide scale. These techniques help us to unravel post-transcriptional regulatory networks. In order to make the visualization of CLIP data easier, we develop cliProfiler package. The cliProfiler includes seven functions which allow users easily make different profile plots.

The cliProfiler package is available at https://bioconductor.org and can be access with the following link: https://bioconductor.org/packages/release/bioc/html/cliProfiler.html.